THOR solves the drawbacks of the current engineering technologies, reproducing complex geometries of native tissues with the combination of cutting-edge technologies:
• self-assembling molecules inspired by the extracellular matrix
• self-assembling polymeric fibres and tubes
• materials functionalization
• cutting-edge mini robots to weave 3D self-assembling structures with factors and cells

THOR tissue arises from high-resolution 3D spatial positioning of biomaterials, angiogenic
factors and relevant cell lineages, reprogrammed and expanded in a dedicated bioreactor
under controlled conditions.

The construction of a functional piece of hippocampal tissue, a structure that is one of the most plastic regions in the mammalian brain.

We aim at creating a precise organization of both neural fibres and vessels, a functioning blood-brain-barrier (BBB) on the microfluidic system with unprecedented life-time expectation (>1 month)